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The early signal substances induced by heat stress in brains of mice

WANG Chunxu, WANG Hanxing

Frontiers of Medicine 2008, Volume 2, Issue 4,   Pages 391-395 doi: 10.1007/s11684-008-0075-1

Abstract: The changes in the expression of cAMP response element binding protein (CREB) and calcitonin gene-related

Keywords: calcitonin gene-related     subsequent ischemia/reperfusion     computer     cerebrum     CGRP excretion    

Potential functions of esophageal cancer-related gene-4 in the cardiovascular system

Rui Zhou, Yuanshu Liu, Wenjun Huang, Xitong Dang

Frontiers of Medicine 2019, Volume 13, Issue 6,   Pages 639-645 doi: 10.1007/s11684-019-0701-0

Abstract: Esophageal cancer-related gene-4 ( ) is cloned from the normal epithelium of the esophagus.correlated with the malignant phenotype of tumor cells, validating that is a real tumor suppressor gene

Keywords: tumor suppressor gene     esophageal cancer-related gene-4     cardiovascular disease     hypoxia    

Influence and related mechanism of Retn gene expression on glucose uptake in 3T3-L1 cells

LI Yahui, DONG Shiyuan, YU Chao, JIANG Yu, LI Huaixing, SUN Shuhan

Frontiers of Medicine 2007, Volume 1, Issue 3,   Pages 269-273 doi: 10.1007/s11684-007-0051-1

Abstract: The aim of this article was to investigate the influence and the related mechanism of the gene on glucoseRadioimmunoassay was used to determine glucose uptake in 3T3-L1 cells with different gene expressionto determine the mRNA levels of several glucose transport proteins in 3T3-L1 cells with different geneThe glucose uptake decreased with the increase in gene expression in 3T3-L1 cells, which was independentResistin could induce insulin resistance in adipocytes, which might be related to the changes of some

Keywords: 3T3-L1     influence     resistance     receptor substrate-1     transport    

Expression profiles of genes and enzymes related to ascorbic acid metabolism in fruits of

Yingying CHEN,Zhihui ZHAO,Jin ZHAO,Mengjun LIU

Frontiers of Agricultural Science and Engineering 2016, Volume 3, Issue 2,   Pages 131-136 doi: 10.15302/J-FASE-2016096

Abstract: The accumulation of AsA, the expression patterns of the nine genes related to AsA metabolism as well

Keywords: Chinese jujube     ascorbic acid     metabolism     gene     enzyme    

Projections of heat-related excess mortality in China due to climate change, population and aging

Frontiers of Environmental Science & Engineering 2023, Volume 17, Issue 11, doi: 10.1007/s11783-023-1732-y

Abstract:

● Four scenarios were used to project heat-related excess mortality

Keywords: Heat-related excess mortality     LMDI     Aging     YLL     VSLY    

Effects and mechanisms of acupuncture on women related health

Frontiers of Medicine doi: 10.1007/s11684-023-1051-5

Abstract: health concern, for those women from developing countries are still struggling with infectious and labor-related

Keywords: acupuncture     women health     clinical efficacy     mechanism    

Study on Family Collection, Gene Mapping, Gene Identification and Gene Function of Human Genetic Diseases

Xia Jiahui

Strategic Study of CAE 2000, Volume 2, Issue 11,   Pages 1-11

Abstract:

In this paper, the study on family collection, gene mapping, gene identification and gene functiont (1; 3) (q44; p11) associated with nasopharyngeal cancer was found in 1975 at first, and human TDF geneIn 1998, GJB3, a human genetic neurological deafness gene, was identified using a novel strategy of “Gene Family-Candidate Disease Gene Cloning”,and the paper was published in Nature Geneticswas also cloned from gene function study.

Keywords: genetic disease     gene mapping and cloning     gene familiy-candidate disease gene cloning     genome wide scan     gene function study    

Advances on immune-related adverse events associated with immune checkpoint inhibitors

Yong Fan, Yan Geng, Lin Shen, Zhuoli Zhang

Frontiers of Medicine 2021, Volume 15, Issue 1,   Pages 33-42 doi: 10.1007/s11684-019-0735-3

Abstract: non-specific activation of effector T cells, ICIs are remarkably associated with a substantial risk of immune-related

Keywords: cancer     immunotherapy     immune checkpoint inhibitors     immune-related adverse events     review    

The critical importance of epigenetics in autoimmune-related skin diseases

Frontiers of Medicine 2023, Volume 17, Issue 1,   Pages 43-57 doi: 10.1007/s11684-022-0980-8

Abstract: Autoimmune-related skin diseases are a group of disorders with diverse etiology and pathophysiology involvedEpigenetics is the study of heritable mechanisms that regulate gene expression without changing DNA sequences, we discuss the most recent findings regarding the function of epigenetic mechanisms in autoimmune-related

Keywords: epigenetics     autoimmune-related skin diseases     DNA methylation     histone modifications     noncoding RNAs    

Obesity-related glomerulopathy: pathogenesis, pathologic, clinical characteristics and treatment

Tianhua Xu, Zitong Sheng, Li Yao

Frontiers of Medicine 2017, Volume 11, Issue 3,   Pages 340-348 doi: 10.1007/s11684-017-0570-3

Abstract: Obesity-related glomerulopathy (ORG) is characterized by glomerulomegaly in the presence or absence of

Keywords: obesity-related glomerulopathy     pathogenesis     pathologic     clinical characteristics    

Molecular engineering of dendrimer nanovectors for siRNA delivery and gene silencing

Yu Cao, Xiaoxuan Liu, Ling Peng

Frontiers of Chemical Science and Engineering 2017, Volume 11, Issue 4,   Pages 663-675 doi: 10.1007/s11705-017-1623-5

Abstract: dendrimers to construct supramolecular dendrimer nanosystems for effective siRNA delivery as well as the related

Keywords: gene therapy     RNAi therapeutics     dendrimer     nanovectors     gene silencing    

Modern developments related to nanotechnology and nanoengineering of concrete

Konstantin SOBOLEV

Frontiers of Structural and Civil Engineering 2016, Volume 10, Issue 2,   Pages 131-141 doi: 10.1007/s11709-016-0343-0

Abstract: This paper reports on modern developments related to nanotechnology of cement and concrete.

Keywords: nanotechnology     cement     concrete     nanoparticle     nano-composite     nanomodification     carbon nanotubes     C-S-H gel     photocatalyst    

Factors related to compliance with oral analgesic treatment of inpatients with chronic pain

Hong Zhu,Yuzhu Zheng,Hui Gao,Li Liu,Lie Yang

Frontiers of Medicine 2015, Volume 9, Issue 3,   Pages 374-379 doi: 10.1007/s11684-015-0411-1

Abstract:

This study aimed to determine the relationship between the different factors of analgesic therapy and the compliance of chronic pain inpatients. We prospectively investigated 100 consecutive inpatients with non-cancer chronic pain who were hospitalized to receive oral analgesic treatment in the Pain Department of West China Hospital from May 2013 to October 2013. Patients who completed the treatment plan were recorded as good compliance, whereas patients who partly completed or even refused the treatment were recorded as moderate or non-compliance, respectively. A total of 73 (73.7%), 17 (17.1%), and 9 (9.2%) patients showed good, moderate, and non-compliance, respectively. Univariate analyses showed significantly better compliance among farmers, patients educated in college or above, with family income of<3000 CNY, and with severe or moderate pain than those employed and unemployed (P=0.02), patients educated below college (P=0.013), with family income of≥3000 CNY (P=0.025), and with mild pain (P<0.001), respectively. Logistic regression analysis showed that the family income of≥3000 CNY (OR: 2.50, 95%CI: 1.65–4.51, P=0.021) and mild pain (OR: 1.27, 95%CI: 1.03–3.31, P=0.016) were associated with moderate or non-compliance with oral analgesic treatment. In conclusion, the low compliance with oral treatment of analgesics was found in Chinese inpatients with chronic pain and compliance was negatively associated with family income and degree of pain of patients.

Keywords: chronic pain     inpatient     oral paregoric drugs     compliance    

The antibiotic resistome: gene flow in environments, animals and human beings

Yongfei Hu, George F. Gao, Baoli Zhu

Frontiers of Medicine 2017, Volume 11, Issue 2,   Pages 161-168 doi: 10.1007/s11684-017-0531-x

Abstract: We propose that the resistance gene flow in nature is “from the natural environments” andand animals, as intermediate recipients and disseminators, contribute greatly to such a resistance gene

Keywords: antibiotic resistance     resistome     microbiome     gene flow    

Reflections on the system of evaluation of gene-edited livestock

Ziyao FAN, Tianwen WU, Kui WU, Yulian MU, Kui LI

Frontiers of Agricultural Science and Engineering 2020, Volume 7, Issue 2,   Pages 211-217 doi: 10.15302/J-FASE-2019303

Abstract: functions regarding economic traits, and new materials for livestock breeding have been obtained through geneEvaluation is the most important component of the regulation of gene-edited livestock and is a crucialguarantee of public safety before the marketing of gene-edited animal products.Here, the system of evaluation of gene-edited livestock is discussed in terms of public safety and production

Keywords: evaluation     gene editing     livestock     performance     safety    

Title Author Date Type Operation

The early signal substances induced by heat stress in brains of mice

WANG Chunxu, WANG Hanxing

Journal Article

Potential functions of esophageal cancer-related gene-4 in the cardiovascular system

Rui Zhou, Yuanshu Liu, Wenjun Huang, Xitong Dang

Journal Article

Influence and related mechanism of Retn gene expression on glucose uptake in 3T3-L1 cells

LI Yahui, DONG Shiyuan, YU Chao, JIANG Yu, LI Huaixing, SUN Shuhan

Journal Article

Expression profiles of genes and enzymes related to ascorbic acid metabolism in fruits of

Yingying CHEN,Zhihui ZHAO,Jin ZHAO,Mengjun LIU

Journal Article

Projections of heat-related excess mortality in China due to climate change, population and aging

Journal Article

Effects and mechanisms of acupuncture on women related health

Journal Article

Study on Family Collection, Gene Mapping, Gene Identification and Gene Function of Human Genetic Diseases

Xia Jiahui

Journal Article

Advances on immune-related adverse events associated with immune checkpoint inhibitors

Yong Fan, Yan Geng, Lin Shen, Zhuoli Zhang

Journal Article

The critical importance of epigenetics in autoimmune-related skin diseases

Journal Article

Obesity-related glomerulopathy: pathogenesis, pathologic, clinical characteristics and treatment

Tianhua Xu, Zitong Sheng, Li Yao

Journal Article

Molecular engineering of dendrimer nanovectors for siRNA delivery and gene silencing

Yu Cao, Xiaoxuan Liu, Ling Peng

Journal Article

Modern developments related to nanotechnology and nanoengineering of concrete

Konstantin SOBOLEV

Journal Article

Factors related to compliance with oral analgesic treatment of inpatients with chronic pain

Hong Zhu,Yuzhu Zheng,Hui Gao,Li Liu,Lie Yang

Journal Article

The antibiotic resistome: gene flow in environments, animals and human beings

Yongfei Hu, George F. Gao, Baoli Zhu

Journal Article

Reflections on the system of evaluation of gene-edited livestock

Ziyao FAN, Tianwen WU, Kui WU, Yulian MU, Kui LI

Journal Article